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At low power, this looks a lot like sprue. yes no?

----Comment by: PathDoc15 on 2/23/2007 11:05:45 AM

That's very astute. The features of villous blunting and crypt hyperplasia do overlap with sprue. We usually say if there's abundant gastric metaplasia and Helicobacter pylori, its likely peptic duodenitis. However, rebiopsy after treatment of the infection would be useful if there was a clinical concern for underlying celiac sprue. A close examination of the surface epithelium for lymphocytes is also in order.

----Comment by: GIPathDoc on 2/23/2007 11:18:10 AM

True I would also corelete with antigliadin antibodies for sprue.

----Comment by: savco on 3/7/2008 1:31:59 PM


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