Additional Info: |
Dermatofibrosarcoma protuberans classically has one of two patterns of invasion into the subcutaneous fat. One pattern is a relatively even layering of fibrous tissue/tumor that penetrates parallel to the surface. The other pattern (shown above) is diffuse infiltration along the septae of the adipocytes. Mixed patterns can be seen. Dermatofibroma, specifically, the deep penetrating variant, can interface with the surrounding fat but this is usually a smooth, well circumscribed boundary, as seen in the deep DF (see folder). When DFs do extend into the fat, it is not extensive and the extensions usually radiate outward focally, like spokes on a wheel. |