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1. Perpendicular orientation of the cell layer is a characteristic of craniopharyngiomas

----Comment by: Npath on 2/15/2011 2:48:34 PM Click to add this comment's arrows to the image above

This is a great image! As I recall, a slow-growing suprasellar tumor that has the ability to recur after excision. Welcome to the site, Npath!

----Comment by: GIPathDoc on 2/15/2011 3:22:54 PM

Npath - Great posts and welcome to the site! Wish I had more to add... perhaps the fact that these tumors have a bimodal distribution in age of diagnosis: one mode is centered in early child hood (<10 years old) and one mode a little later (50-60 yo). There is probably something interesting molecularly here, just not sure what it is. Also "wet keratin" rings a bell as an aid in diagnosis - but I don't think it is evident in the photo.

----Comment by: PathDoc15 on 2/15/2011 6:22:12 PM

     

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